Rabbit anti-SA2 Antibody, Affinity Purified
Brand:
A302-580A-M
- Brand
- Bethyl Laboratories
- Application
- IHC
IP
WB
- Storage Conditions
- 2 - 8° C
- Host
- Rabbit
- Conjugation
- Unconjugated
- Immunogen
- between 1 and 50
- Buffer
- Tris-buffered Saline containing 0.1% BSA and 0.09% Sodium Azide
- Reactivity
- Human
- Target
- SA2
- Shelf Life
- 1 year from date of receipt
- Antibody Type
- Polyclonal
- Alternate Names
- bA517O1.1, cohesin subunit SA-2, SA2, SA-2, SCC3 homolog 2, SCC3B, Stromal antigen 2
- Format
- Whole IgG
- Presumed Reactivity
- Based on 100% sequence identity, this antibody is predicted to react with Mouse
- Product Type
- Primary Antibodies
- Product Sub Types
- Primary Antibodies
- UNSPSC
- 12352203
- Western Blot (WB)
- 1:2,000 - 1:10,000
- Immunoprecipitation (IP)
- 2 - 5 µg/mg lysate
- Immunohistochemistry (IHC)
- 1:500 - 1:2,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
- Target Sentence
- SA2 is a component of the multisubunit cohesin complex. Cohesin functions to hold sister chromatids together during meiosis and mitosis and ensure proper segregation of chromosomes. Cohesin must dissociate from sister chromatids during prophase and metaphase so that they can segregate to opposite poles of the cell during anaphase. As part of the cohesin complex, SA2 appears to play a role in cohesin dissociation required for sister chromatid separation. Interestingly, SA2 has been demonstrated to also exhibit transcriptional regulatory activity through an association with NF-kappaB.
- Product Link
- http://www.bethyl.com/product/A302-580A
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