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Rabbit anti-SAE2 Antibody, Affinity Purified

Catalog No.
A302-925A-M
Pack Size
  • 20 µl (2 blots)
  • 100 µl (10 blots)
  • 100 µl (200 µg/ml)
Quantity
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Brand:
Specifications
A302-925A-M
Brand
Bethyl Laboratories
Application
IHC
IP
WB
Storage Conditions
2 - 8° C
Host
Rabbit
Conjugation
Unconjugated
Immunogen
Between 525 and 575
Buffer
Tris-buffered Saline containing 0.1% BSA and 0.09% Sodium Azide
Reactivity
Human, Mouse
Target
SAE2
Shelf Life
1 year from date of receipt
Antibody Type
Polyclonal
Alternate Names
anthracycline-associated resistance ARX, ARX, HRIHFB2115, SAE2, SUMO1 activating enzyme subunit 2, SUMO-1 activating enzyme subunit 2, SUMO-activating enzyme subunit 2, UBA2, ubiquitin-activating enzyme E1 homolog, ubiquitin-like 1-activating enzyme E1B, Ubiquitin-like modifier-activating enzyme 2
Format
Whole IgG
Product Type
Primary Antibodies
Product Sub Types
Primary Antibodies
UNSPSC
12352203
Western Blot (WB)
1:2,000 - 1:10,000
Immunoprecipitation (IP)
2 - 5 µg/mg lysate
Immunohistochemistry (IHC)
1:100 - 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
Target Sentence
SAE2 (SUMO-activating enzyme subunit 2) is also known as UBA2 (ubiquitin-like modifier activating enzyme 2). Heterodimers of SAE1 and SAE2 act as an E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. Heterodimers mediate ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2 [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/ Q9UBT2].
Product Link
http://www.bethyl.com/product/A302-925A
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