Rabbit anti-SARA Antibody, Affinity Purified
Brand:
A303-768A-M
- Brand
- Bethyl Laboratories
- Application
- IP
WB
- Storage Conditions
- 2 - 8° C
- Host
- Rabbit
- Conjugation
- Unconjugated
- Immunogen
- between 1 and 50
- Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide
- Reactivity
- Human
- Target
- SARA
- Shelf Life
- 1 year from date of receipt
- Antibody Type
- Polyclonal
- Alternate Names
- hSARA, MAD, mothers against decapentaplegic homolog interacting protein, receptor activation anchor, MADH-interacting protein, MADHIP, Mothers against decapentaplegic homolog-interacting protein, novel serine protease, NSP, PPP1R173, protein phosphatase 1, regulatory subunit 173, Receptor activation anchor, SARA, smad anchor for receptor activation, SMADIP, zinc finger FYVE domain-containing protein 9, zinc finger, FYVE domain containing 9
- Format
- Whole IgG
- Product Type
- Primary Antibodies
- Product Sub Types
- Primary Antibodies
- UNSPSC
- 12352203
- Western Blot (WB)
- 1:2,000 - 1:10,000
- Immunoprecipitation (IP)
- 2 - 10 µg/mg lysate
- Target Sentence
- Smad anchor for receptor activation (SARA) is an early endosomal protein that functions to recruit SMAD2/SMAD3 to intracellular membranes and to the TGF-beta receptor. SARA plays a significant role in TGF-mediated signaling by regulating the subcellular location of SMAD2 and SMAD3 and modulating the transcriptional activity of the SMAD3/SMAD4 complex. SARA is possibly associated with TGF-beta receptor internalization [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/O95405].
- Product Link
- http://www.bethyl.com/product/A303-768A
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