A303-554A-M
- Brand
- Bethyl Laboratories
- Application
- IP
WB
- Storage Conditions
- 2 - 8° C
- Host
- Rabbit
- Conjugation
- Unconjugated
- Immunogen
- between 450 and 500
- Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide
- Reactivity
- Human
- Target
- SCAP
- Shelf Life
- 1 year from date of receipt
- Antibody Type
- Polyclonal
- Alternate Names
- SCAP, SREBP cleavage-activating protein, sterol regulatory element-binding protein cleavage-activating protein
- Format
- Whole IgG
- Product Type
- Primary Antibodies
- Product Sub Types
- Primary Antibodies
- UNSPSC
- 12352203
- Western Blot (WB)
- 1:2,000 - 1:10,000
- Immunoprecipitation (IP)
- 2 - 10 µg/mg lysate
- Target Sentence
- Sterol regulatory element-binding protein cleavage-activating protein (SCAP) is a protein with a sterol sensing domain (SSD) and seven WD domains. In the presence of cholesterol, SCAP binds to sterol regulatory element binding proteins (SREBPs) and mediates their transport from the ER to the Golgi. The SREBPs are then proteolytically cleaved and regulate sterol biosynthesis [taken from NCBI Entrez Gene (Gene ID: 22937)].
- Product Link
- http://www.bethyl.com/product/A303-554A