Rabbit anti-SF3a120/SAP114 Antibody, Affinity Purified
Brand:
A301-602A-M
- Brand
- Bethyl Laboratories
- Application
- IHC
IP
WB
- Storage Conditions
- 2 - 8° C
- Host
- Rabbit
- Conjugation
- Unconjugated
- Immunogen
- between 350 and 400
- Buffer
- Tris-buffered Saline containing 0.1% BSA and 0.09% Sodium Azide
- Reactivity
- Human, Mouse
- Target
- SF3a120/SAP114
- Shelf Life
- 1 year from date of receipt
- Antibody Type
- Polyclonal
- Alternate Names
- pre-mRNA processing 21, pre-mRNA splicing factor SF3a (120 kDa subunit), PRP21, PRPF21, SAP 114, SAP114, SF3A120, spliceosome-associated protein 114, splicing factor 3 subunit 1, splicing factor 3A subunit 1, splicing factor 3a, subunit 1, 120kD, splicing factor 3a, subunit 1, 120kDa
- Format
- Whole IgG
- Presumed Reactivity
- Based on 100% sequence identity, this antibody is predicted to react with Bovine
- Product Type
- Primary Antibodies
- Product Sub Types
- Primary Antibodies
- UNSPSC
- 12352203
- Western Blot (WB)
- 1:2,000 - 1:10,000
- Immunoprecipitation (IP)
- 2 - 5 µg/mg lysate
- Immunohistochemistry (IHC)
- 1:200 - 1:1,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
- Target Sentence
- SF3a120/SAP114 is a 120 kDa subunit of the heterotrimeric splicing factor 3a (SF3A) protein complex. SF3A along with SF3B and a 12S RNA subunit are components of the 17S U2 small nuclear ribonucleoprotein complex (U2 snRNP) involved in pre-mRNA splicing. SF3a120/SAP114 bears two SURP motif repeats and one ubiquitin-like domain. SURP motifs are found among proteins involved in regulated mRNA splicing. The SURP motifs along with the ubiquitin-like domain of SF3a120/SAP114 appear to function in the heterotrimeric formation between the 120, 60 and 66 kDa subunits.
- Product Link
- http://www.bethyl.com/product/A301-602A
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