Rabbit anti-SIL Antibody, Affinity Purified
Brand:
A302-441A-M
- Brand
- Bethyl Laboratories
- Application
- IP
WB
- Storage Conditions
- 2 - 8° C
- Host
- Rabbit
- Conjugation
- Unconjugated
- Immunogen
- between 450 and 500
- Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide
- Reactivity
- Human
- Target
- SIL
- Shelf Life
- 1 year from date of receipt
- Antibody Type
- Polyclonal
- Alternate Names
- MCPH7, SCL/TAL1 interrupting locus, SCL-interrupting locus protein, SIL, TAL-1-interrupting locus protein
- Format
- Whole IgG
- Product Type
- Primary Antibodies
- Product Sub Types
- Primary Antibodies
- UNSPSC
- 12352203
- Western Blot (WB)
- 1:10,000 - 1:25,000
- Immunoprecipitation (IP)
- 2 - 10 µg/mg lysate
- Target Sentence
- SCL-interrupting locus (SIL) plays an important role in embryonic development as well as in cellular growth and proliferation. The long-term silencing of SIL affects cell survival and cell cycle distribution as well as decreases CDC2 activity correlated with reduced phosphorylation of CDC2. SIL is a positive regulator of the sonic hedgehog pathway, acting downstream of PTCH1. [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q15468].
- Product Link
- http://www.bethyl.com/product/A302-441A
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