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Rabbit anti-SIRP alpha Recombinant Monoclonal Antibody [BLR049F]
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Brand:
A700-049-T
- Brand
- Bethyl Laboratories
- Application
- ICC
IHC
IP
WB
- Storage Conditions
- 2 - 8° C
- Host
- Rabbit
- Conjugation
- Unconjugated
- Immunogen
- residues 31-368 (ECD)
- Buffer
- Borate Buffered Saline (BBS) pH 8.2 with 0.1% BSA and 0.09% Sodium Azide
- Reactivity
- Human
- Target
- SIRP alpha
- Shelf Life
- 1 year from date of receipt
- Antibody Type
- Recombinant Monoclonal
- Alternate Names
- BIT, Brain Ig-like molecule with tyrosine-based activation motifs, brain-immunoglobulin-like molecule with tyrosine-based activation motifs, CD antigen CD172a, CD172 antigen-like family member A, CD172A, inhibitory receptor SHPS-1, macrophage fusion receptor, MFR, MYD-1, myd-1 antigen, P84, PTPNS1, SHP substrate 1, SHPS1, SHPS-1, Signal-regulatory protein alpha-1, Signal-regulatory protein alpha-2, Signal-regulatory protein alpha-3, SIRP, Sirp-alpha-1, Sirp-alpha-2, Sirp-alpha-3, tyrosine phosphatase SHP substrate 1, tyrosine-protein phosphatase non-receptor type substrate 1
- Format
- Whole IgG
- Product Type
- Primary Antibodies
- Product Sub Types
- Primary Antibodies
- UNSPSC
- 12352203
- Western Blot (WB)
- 1:1000
- Immunoprecipitation (IP)
- 20 µl/1 mg lysate
- Immunohistochemistry (IHC)
- 1:100 to 1:500. Epitope retrieval with citrate buffer pH6.0 is recommended for FFPE tissue sections.
- Immunocytochemistry (ICC)
- 1:100 to 1:500. Epitope retrieval with citrate buffer pH6.0 is recommended for FFPE cell sections.
- Target Sentence
- SIRP alpha is a member of the signal-regulatory-protein (SIRP) family, and also belongs to the immunoglobulin superfamily. SIRP family members are receptor-type transmembrane glycoproteins known to be involved in the negative regulation of receptor tyrosine kinase-coupled signaling processes. SIRP alpha is a cell surface receptor for CD47 and CD47 binding prevents maturation of immature dendritic cells and inhibits cytokine production by mature dendritic cells. [taken from NCBI Entrez Gene (Gene ID: 140885)].
- Product Link
- http://www.bethyl.com/product/A700-049
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