Rabbit anti-SMARCD1/BAF60a Antibody, Affinity Purified
Brand:
A301-595A-T
- Brand
- Bethyl Laboratories
- Application
- IP
WB
- Storage Conditions
- 2 - 8° C
- Host
- Rabbit
- Conjugation
- Unconjugated
- Immunogen
- between 250 and 300
- Buffer
- Tris-buffered Saline containing 0.1% BSA and 0.09% Sodium Azide
- Reactivity
- Human, Mouse
- Target
- SMARCD1/BAF60a
- Shelf Life
- 1 year from date of receipt
- Antibody Type
- Polyclonal
- Alternate Names
- 60 kDa BRG-1/Brm-associated factor subunit A, BAF60A, BRG1-associated factor 60A, chromatin remodeling complex BAF60A subunit, CRACD1, mammalian chromatin remodeling complex BRG1-associated factor 60A, Rsc6p, SWI/SNF complex 60 kDa subunit, SWI/SNF complex 60 kDa subunit A, SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1, Swp73-like protein
- Format
- Whole IgG
- Presumed Reactivity
- Based on 100% sequence identity, this antibody is predicted to react with Bovine
- Product Type
- Primary Antibodies
- Product Sub Types
- Primary Antibodies
- UNSPSC
- 12352203
- Western Blot (WB)
- 1:500 - 1:2,500
- Immunoprecipitation (IP)
- Not recommended. Use rabbit anti-SMARCD1/BAF60a antibody A301-594A.
- Target Sentence
- The SMARCs (SWI/SNF-related, matrix-associated, actin-dependent regulators of chromatin), and BAFs (BRG1-associated factors), have been identified as components of the mammalian SWI/SNF-like chromatin-remodeling protein complexes. These multi-protein complexes are proposed to function as ATP-driven motors that translocate along DNA and destabilize nucleosomal structures to facilitate transcription factor binding. SMARCD1/BAF60a is subunit of the SWI/SNF complex that has been identified as a factor that interacts with nuclear receptors such as the vitamin D receptor and glucocorticoid receptor and a subset of Fos/Jun dimers. SMARCD1 has also been shown to interact with p53 and is suggested to be involved in the tumor suppressor activity of p53. From these findings it has been concluded that SMARCD1 functions as a direct link between transcription factors and SWI/SNF remodeling activity to regulate transcription.
- Product Link
- http://www.bethyl.com/product/A301-595A
Related products
