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Rabbit anti-SMC1 Recombinant Monoclonal Antibody [BL-205-2G8]

Catalog No.
A700-018-T
Pack Size
  • 20 µl (2 blots)
  • 100 µl (10 blots)
Quantity
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Brand:
Specifications
A700-018-T
Brand
Bethyl Laboratories
Application
F
ICC
IHC
IHC-IF
IP
WB
Storage Conditions
2 - 8° C
Host
Rabbit
Conjugation
Unconjugated
Immunogen
between 1200 to 1233 (C-term)
Buffer
Borate Buffered Saline (BBS) pH 8.2 with 0.1% BSA and 0.09% Sodium Azide
Reactivity
Human, Mouse
Target
SMC1
Shelf Life
1 year from date of receipt
Antibody Type
Recombinant Monoclonal
Alternate Names
CDLS2, DXS423E, epididymis secretory sperm binding protein, SB1.8, segregation of mitotic chromosomes 1, SMC protein 1A, SMC1, SMC1 (structural maintenance of chromosomes 1, yeast)-like 1, SMC-1A, SMC1alpha, SMC-1-alpha, SMC1L1, SMCB, structural maintenance of chromosomes protein 1A
Format
Whole IgG
Presumed Reactivity
Based on 100% sequence identity, this antibody is predicted to react with Rat and Bovine
Product Type
Primary Antibodies
Product Sub Types
Primary Antibodies
UNSPSC
12352203
Western Blot (WB)
1:1000
Immunoprecipitation (IP)
20 µl/mg lysate
Immunohistochemistry (IHC)
1:100 - 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
Immunocytochemistry (ICC)
1:100 - 1:500. Epitope retrieval with citrate buffer pH6.0 is recommended for FFPE cell sections.
Immunohistochemistry-Immunofluoresence (IHC-IF)
1:100 - 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
Flow Cytometry (F)
Fixed in 4% formaldehyde and permeabilized with 90% methanol. 1 µl per 1 x 10^6 cells.
Target Sentence
Structural maintenance of chromosomes (SMC) proteins are part of the cohesin and condensin multisubunit complexes that play a critical role in chromosome organization, segregation, gene regulation, and DNA repair. The core cohesin complex includes a heterodimer of SMC1 and SMC3 that functions by forming a ring-like structure that holds sister chromatids together. Cohesin is important to sister chromatid separation and segregation during mitosis and meiosis and also plays a role in double-strand break repair by homologous recombination.
Product Link
http://www.bethyl.com/product/A700-018
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