Rabbit anti-Spt16 Antibody, Affinity Purified
Brand:
A302-492A-M
- Brand
- Bethyl Laboratories
- Application
- IP
WB
- Storage Conditions
- 2 - 8° C
- Host
- Rabbit
- Conjugation
- Unconjugated
- Immunogen
- between 997 and 1047
- Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide
- Reactivity
- Human
- Target
- Spt16
- Shelf Life
- 1 year from date of receipt
- Antibody Type
- Polyclonal
- Alternate Names
- CDC68, chromatin-specific transcription elongation factor 140 kDa subunit, facilitates chromatin remodeling 140 kDa subunit, facilitates chromatin transcription complex subunit SPT16, FACT 140 kDa subunit, FACT complex subunit SPT16, FACTP140, hSPT16, SPT16, SPT16/CDC68, suppressor of Ty 16 homolog
- Format
- Whole IgG
- Presumed Reactivity
- Based on 100% sequence identity, this antibody is predicted to react with Mouse
- Product Type
- Primary Antibodies
- Product Sub Types
- Primary Antibodies
- UNSPSC
- 12352203
- Western Blot (WB)
- 1:2,000 - 1:10,000
- Immunoprecipitation (IP)
- Not recommended
- Target Sentence
- Spt16 is a Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is composed of two subunits: SSRP1 and Spt16. It is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, and then subsequently promotes the reestablishment of the nucleosome following the passage of RNA polymerase II [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q9Y5B9].
- Product Link
- http://www.bethyl.com/product/A302-492A
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