Rabbit anti-SPTLC1 Antibody, Affinity Purified
Brand:
A303-408A-M
- Brand
- Bethyl Laboratories
- Application
- IP
WB
- Storage Conditions
- 2 - 8° C
- Host
- Rabbit
- Conjugation
- Unconjugated
- Immunogen
- between 423 and 473
- Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide
- Reactivity
- Human
- Target
- SPTLC1
- Shelf Life
- 1 year from date of receipt
- Antibody Type
- Polyclonal
- Alternate Names
- HSAN1, HSN1, LBC1, LCB 1, LCB1, long chain base biosynthesis protein 1, serine C-palmitoyltransferase, serine palmitoyltransferase 1, serine-palmitoyl-CoA transferase 1, SPT 1, SPT1, SPTI
- Format
- Whole IgG
- Presumed Reactivity
- Based on 100% sequence identity, this antibody is predicted to react with Orangutan
- Product Type
- Primary Antibodies
- Product Sub Types
- Primary Antibodies
- UNSPSC
- 12352203
- Western Blot (WB)
- 1:2,000 - 1:10,000
- Immunoprecipitation (IP)
- 2 - 10 µg/mg lysate
- Target Sentence
- Serine palmitoyltransferase (SPT), which consists of two different subunits, is the key enzyme in sphingolipid biosynthesis. It converts L-serine and palmitoyl-CoA to 3-oxosphinganine with pyridoxal 5'-phosphate as a cofactor. SPTLC1 (serine palmitoyltransferase, long chain base subunit 1 is the long chain base subunit 1 of serine palmitoyltransferase. Mutations in SPTLC1 were identified in patients with hereditary sensory neuropathy type 1 [taken from NCBI Entrez Gene (Gene ID: 10558)].
- Product Link
- http://www.bethyl.com/product/A303-408A
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