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Rabbit anti-SS-B Antibody, Affinity Purified

Catalog No.
A303-902A-M
Pack Size
  • 20 µl (2 blots)
  • 100 µl (10 blots)
  • 100 µl (1000 µg/ml)
Quantity
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Brand:
Specifications
A303-902A-M
Brand
Bethyl Laboratories
Application
IHC
IP
WB
Storage Conditions
2 - 8° C
Host
Rabbit
Conjugation
Unconjugated
Immunogen
Between 358 and 408
Buffer
Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide
Reactivity
Human
Target
SS-B
Shelf Life
1 year from date of receipt
Antibody Type
Polyclonal
Alternate Names
autoantigen La, La, la autoantigen, La ribonucleoprotein, La ribonucleoprotein domain family, member 3, La/SSB, LARP3, lupus La antigen, lupus La protein, sjoegren syndrome type B antigen, SS-B, SS-B/La protein
Format
Whole IgG
Presumed Reactivity
Based on 100% sequence identity, this antibody is predicted to react with Bovine and Rabbit
Product Type
Primary Antibodies
Product Sub Types
Primary Antibodies
UNSPSC
12352203
Western Blot (WB)
1:2,000 - 1:10,000
Immunoprecipitation (IP)
Not recommended
Immunohistochemistry (IHC)
1:2,000 - 1:10,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
Target Sentence
Sjogren syndrome antigen B (autoantigen La) (SS-B) is involved in diverse aspects of RNA metabolism, including binding and protecting poly(U) termini of nascent RNA polymerase III transcripts from exonuclease digestion, processing 5' and 3' ends of pre-tRNA precursors, acting as an RNA chaperone, and binding viral RNAs associated with hepatitis C virus. Autoantibodies reacting with this protein are found in the sera of patients with Sjogren syndrome and systemic lupus erythematosus [taken from NCBI Entrez Gene (Gene ID: 6741)].
Product Link
http://www.bethyl.com/product/A303-902A
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