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Rabbit anti-STAT5b Recombinant Monoclonal Antibody [BLR146J]

Catalog No.
A700-146-T
Pack Size
  • 10 µl (5+ tests)
  • 100 µl (50+ tests)
Quantity
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Brand:
Specifications
A700-146-T
Brand
Bethyl Laboratories
Application
ICC
IHC
IP
WB
Storage Conditions
2 - 8° C
Host
Rabbit
Conjugation
Unconjugated
Immunogen
between 737 and 787 (C-term)
Buffer
Borate Buffered Saline (BBS) pH 8.2 with 0.09% Sodium Azide, BSA Free
Reactivity
Human, Mouse
Target
STAT5b
Shelf Life
1 year from date of receipt
Antibody Type
Recombinant Monoclonal
Alternate Names
signal transducer and activator of transcription 5B, STAT5, transcription factor STAT5B
Format
Whole IgG
Product Type
Primary Antibodies
Product Sub Types
Primary Antibodies
UNSPSC
12352203
Western Blot (WB)
1:1,000
Immunoprecipitation (IP)
6 µl/1 mg lysate
Immunohistochemistry (IHC)
1:100 to 1:500. Epitope retrieval with citrate buffer pH6.0 is recommended for FFPE tissue sections.
Immunocytochemistry (ICC)
1:100 to 1:500. Epitope retrieval with citrate buffer pH6.0 is recommended for FFPE cell sections.
Target Sentence
Signal transducer and activator of transcription 5b (STAT5b) is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. STAT5A mediates the signal transduction triggered by various cell ligands, such as IL2, IL4, CSF1, and different growth hormones. It has been shown to be involved in diverse biological processes, such as TCR signaling, apoptosis, adult mammary gland development, and sexual dimorphism of liver gene expression [taken from NCBI Entrez Gene (Gene ID: 6777)].
Product Link
http://www.bethyl.com/product/A700-146
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