Rabbit anti-SUZ12 Antibody, Affinity Purified
Brand:
A302-407A-M
- Brand
- Bethyl Laboratories
- Application
- IP
WB
- Storage Conditions
- 2 - 8° C
- Host
- Rabbit
- Conjugation
- Unconjugated
- Immunogen
- Between 689 and 739
- Buffer
- Tris-buffered Saline containing 0.1% BSA and 0.09% Sodium Azide
- Reactivity
- Human, Mouse
- Target
- SUZ12
- Shelf Life
- 1 year from date of receipt
- Antibody Type
- Polyclonal
- Alternate Names
- chET 9 protein, CHET9, chromatin precipitated E2F target 9 protein, JJAZ1, joined to JAZF1 protein, polycomb protein SUZ12, suppressor of zeste 12 protein homolog
- Format
- Whole IgG
- Product Type
- Primary Antibodies
- Product Sub Types
- Primary Antibodies
- UNSPSC
- 12352203
- Western Blot (WB)
- 1:2,000 - 1:10,000
- Immunoprecipitation (IP)
- 2 - 5 µg/mg lysate
- Target Sentence
- SUZ12 (suppressor of zeste 12) is the human homolog of the drosophila SUZ12 gene. SUZ12 is a Polycomb group (PcG) protein and a component of the PRC2/EED-EZH2 complex, which methylates 'Lys-9' and 'Lys-27' of histone H3, leading to transcriptional repression of the affected target gene. A chromosomal aberration, t(7;17)(p15;q21), involving SUZ12 and JAZF1 may be a cause of endometrial stromal tumors. The translocation generates the JAZF1-SUZ12 oncogene consisting of the N-terminus part of JAZF1 and the C-terminus part of SUZ12. It is frequently found in all cases of endometrial stromal tumors, except in endometrial stromal sarcomas, where it is rarer [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q15022].
- Product Link
- http://www.bethyl.com/product/A302-407A
Related products
