A305-450A-T
- Brand
- Bethyl Laboratories
- Application
- IP
- Storage Conditions
- 2 - 8° C
- Host
- Rabbit
- Conjugation
- Unconjugated
- Immunogen
- between 425 and 475
- Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide
- Reactivity
- Human
- Target
- TBCE
- Shelf Life
- 1 year from date of receipt
- Antibody Type
- Polyclonal
- Alternate Names
- HRD, hypoparathyroidism, growth and mental retardation, and dysmorphism, KCS, KCS1, pac2, PEAMO, Tubulin-folding cofactor E, tubulin-specific chaperone E
- Format
- Whole IgG
- Presumed Reactivity
- Based on 100% sequence identity, this antibody is predicted to react with Orangutan
- Product Type
- Primary Antibodies
- Product Sub Types
- Primary Antibodies
- UNSPSC
- 12352203
- Western Blot (WB)
- Not recommended. A305-450A has not performed satisfactorily when used for WB of TBCE in crude preparations (e.g. whole cell lysate). This antibody can be used for WB of enriched (e.g. immunoprecipitated) sources of TBCE.
- Immunoprecipitation (IP)
- 2 - 10 µg/mg lysate
- Target Sentence
- Tubulin folding Cofactor E (TBCE) is one of four proteins (cofactors A, D, E, and C) involved in the pathway leading to correctly folded beta-tubulin from folding intermediates. Cofactors A and D are believed to play a role in capturing and stabilizing beta-tubulin intermediates in a quasi-native confirmation. Cofactor E binds to the cofactor D/beta-tubulin complex; interaction with cofactor C then causes the release of beta-tubulin polypeptides that are committed to the native stat.[taken from NCBI Entrez Gene (Gene ID: 6905)].
- Product Link
- http://www.bethyl.com/product/A305-450A