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Rabbit anti-TCEB2 Antibody, Affinity Purified

Catalog No.
A304-008A-T
Pack Size
  • 100 µl (1000 µg/ml)
  • 10 µl (1000 µg/ml)
Quantity
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Brand:
Specifications
A304-008A-T
Brand
Bethyl Laboratories
Application
IHC
IP
WB
Storage Conditions
2 - 8° C
Host
Rabbit
Conjugation
Unconjugated
Immunogen
Between 68 and 118
Buffer
Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide
Reactivity
Human, Mouse
Target
TCEB2
Shelf Life
1 year from date of receipt
Antibody Type
Polyclonal
Alternate Names
EloB, elongin 18 kDa subunit, elongin, 18-kD subunit, elongin-B, epididymis secretory sperm binding protein, RNA polymerase II transcription factor SIII p18 subunit, RNA polymerase II transcription factor SIII subunit B, SIII, SIII p18, TCEB2, transcription elongation factor B (SIII), polypeptide 2 (18kDa, elongin B), transcription elongation factor B polypeptide 2, transcription elongation factor B subunit 2
Format
Whole IgG
Product Type
Primary Antibodies
Product Sub Types
Primary Antibodies
UNSPSC
12352203
Western Blot (WB)
1:500 - 1:2,500
Immunoprecipitation (IP)
2 - 10 µg/mg lysate
Immunohistochemistry (IHC)
1:1,000 - 1:5,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
Target Sentence
TCEB2, also known as Elongin B, is a subunit of the transcription factor B (SIII) complex. The SIII complex is composed of elongins A/A2, B and C. It activates elongation by RNA polymerase II by suppressing transient pausing of the polymerase at many sites within transcription units. Elongin A functions as the transcriptionally active component of the SIII complex, whereas elongins B and C are regulatory subunits. Elongin A2 is specifically expressed in the testis, and capable of forming a stable complex with elongins B and C. The von Hippel-Lindau tumor suppressor protein binds to elongins B and C, and thereby inhibits transcription elongation [taken from NCBI Entrez Gene (Gene ID: 6923)].
Product Link
http://www.bethyl.com/product/A304-008A
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