Rabbit anti-Treslin Antibody, Affinity Purified
Brand:
A303-472A-M
- Brand
- Bethyl Laboratories
- Application
- IP
WB
- Storage Conditions
- 2 - 8° C
- Host
- Rabbit
- Conjugation
- Unconjugated
- Immunogen
- between 975 and 1025
- Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide
- Reactivity
- Human
- Target
- Treslin
- Shelf Life
- 1 year from date of receipt
- Antibody Type
- Polyclonal
- Alternate Names
- C15orf42, SLD3, topBP1-interacting checkpoint and replication regulator, topBP1-interacting replication-stimulating protein, TopBP1-interacting, replication-stimulating protein, Treslin
- Format
- Whole IgG
- Product Type
- Primary Antibodies
- Product Sub Types
- Primary Antibodies
- UNSPSC
- 12352203
- Western Blot (WB)
- 1:500 - 1:2,500
- Immunoprecipitation (IP)
- Not recommended
- Target Sentence
- Treslin is a regulator of DNA replication and S/M and G2/M checkpoints. Treslin regulates the triggering of DNA replication initiation via its interaction with TOPBP1 by participating in CDK2-mediated loading of CDC45L onto replication origins. Treslin is required for the transition from pre-replication complex (pre-RC) to pre-initiation complex (pre-IC) and for the prevention of mitotic entry after treatment with ionizing radiation [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q7Z2Z1].
- Product Link
- http://www.bethyl.com/product/A303-472A
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