Rabbit anti-TRPC6 Antibody, Affinity Purified
Brand:
A303-024A-M
- Brand
- Bethyl Laboratories
- Application
- IP
WB
- Storage Conditions
- 2 - 8° C
- Host
- Rabbit
- Conjugation
- Unconjugated
- Immunogen
- between 350 and 400
- Buffer
- Tris-buffered Saline containing 0.1% BSA and 0.09% Sodium Azide
- Reactivity
- Human
- Target
- TRPC6
- Shelf Life
- 1 year from date of receipt
- Antibody Type
- Polyclonal
- Alternate Names
- focal segmental glomerulosclerosis 2, FSGS2, short transient receptor potential channel 6, transient receptor protein 6, TRP6, TRP-6, TrpC6
- Format
- Whole IgG
- Product Type
- Primary Antibodies
- Product Sub Types
- Primary Antibodies
- UNSPSC
- 12352203
- Western Blot (WB)
- 1:2,000 - 1:10,000
- Immunoprecipitation (IP)
- 2 - 5 µg/mg lysate
- Target Sentence
- TRPC6 (transient receptor potential cation channel, subfamily C, member 6) forms a receptor-activated calcium channel in the cell membrane. The channel is activated by diacylglycerol and is thought to be under the control of a phosphatidylinositol second messenger system. Activation of this channel occurs independently of protein kinase C and is not triggered by low levels of intracellular calcium. Defects in the TRPC6 gene are a cause of focal segmental glomerulosclerosis 2 (FSGS2) [taken from NCBI Entrez Gene (Gene ID: 7225].
- Product Link
- http://www.bethyl.com/product/A303-024A
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