A300-414A-M
- Brand
- Bethyl Laboratories
- Application
- IP
WB
- Storage Conditions
- 2 - 8° C
- Host
- Rabbit
- Conjugation
- Unconjugated
- Immunogen
- between 650 and 700
- Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide
- Reactivity
- Human
- Target
- TRPM2
- Shelf Life
- 1 year from date of receipt
- Antibody Type
- Polyclonal
- Alternate Names
- EREG1, estrogen-responsive element-associated gene 1 protein, KNP3, long transient receptor potential channel 2, LTRPC2, LTrpC-2, NUDT9H, NUDT9L1, transient receptor potential cation channel subfamily M member 2, transient receptor potential channel 7, transient receptor potential melastatin 2, TRPC7
- Format
- Whole IgG
- Presumed Reactivity
- Based on 100% sequence identity, this antibody is predicted to react with Mouse
- Product Type
- Primary Antibodies
- Product Sub Types
- Primary Antibodies
- UNSPSC
- 12352203
- Western Blot (WB)
- 1:2,000 - 1:10,000
- Immunoprecipitation (IP)
- 2 - 10 µg/mg lysate
- Target Sentence
- TRPM2 (transient receptor potential cation channel subfamily M member 2) is a voltage-independent cation channel that mediates susceptibility to cell death in response to oxidative stress. TRPM2 is activated by adenosine diphosphoribose (ADP-ribose) and its activation is dependent on calcium and calmodulin levels. A splice variant of TRPM2, TRPM2-S, has been shown to interact with the full length form and suppress calcium influx and susceptibility to cell death.
- Product Link
- http://www.bethyl.com/product/A300-414A