Rabbit anti-UVRAG IHC Antibody, Affinity Purified
Brand:
IHC-00590-T
- Brand
- Bethyl Laboratories
- Application
- IHC
- Storage Conditions
- 2 - 8° C
- Host
- Rabbit
- Conjugation
- Unconjugated
- Immunogen
- Between 649 and 699
- Buffer
- Tris-buffered Saline containing 0.1% BSA and 0.09% Sodium Azide
- Reactivity
- Human, Mouse
- Target
- UVRAG
- Shelf Life
- 1 year from date of receipt
- Antibody Type
- Polyclonal
- Alternate Names
- beclin 1 binding protein, DHTX, disrupted in heterotaxy, p63, UV radiation resistance-associated gene protein, VPS38
- Format
- Whole IgG
- Product Type
- Primary Antibodies
- Product Sub Types
- Primary Antibodies
- UNSPSC
- 12352203
- Immunohistochemistry (IHC)
- 1:100 - 1:500
- Target Sentence
- UV radiation resistance associated gene (UVRAG) was first identified as a gene that could complement UV sensitivity in xeroderma pigmentosum cells. UVRAG may have tumor suppressor activity as mutations in the UVRAG gene have been associated with various human colon cancer cells and tissues. UVRAG has been shown to interact with Beclin 1 (Bcl-2-interacting protein), a protein that forms a complex with class III PI-3-kinase (PI3KC3) and is involved in autophagy. In this complex, UVRAG is proposed to function as a positive regulator of autophagy and a negative regulator of the growth of tumor cells.
- Product Link
- http://www.bethyl.com/product/IHC-00590-T
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