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Rabbit anti-VTA1/LIP5 Antibody, Affinity Purified

Catalog No.
A304-828A-M
Pack Size
  • 20 µl (2 blots)
  • 100 µl (10 blots)
  • 100 µl (1000 µg/ml)
Quantity
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Brand:
Specifications
A304-828A-M
Brand
Bethyl Laboratories
Application
IP
WB
Storage Conditions
2 - 8° C
Host
Rabbit
Conjugation
Unconjugated
Immunogen
between 150 and 200
Buffer
Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide
Reactivity
Human
Target
VTA1/LIP5
Shelf Life
1 year from date of receipt
Antibody Type
Polyclonal
Alternate Names
C6orf55, dopamine-responsive gene 1 protein, DRG1, DRG-1, homolog of mouse SKD1-binding protein 1, HSPC228, LIP5, LYST-interacting protein 5, My012, SBP1, SKD1-binding protein 1, vacuolar protein sorting-associated protein VTA1 homolog, vesicle (multivesicular body) trafficking 1, Vps20-associated 1 homolog
Format
Whole IgG
Presumed Reactivity
Based on 100% sequence identity, this antibody is predicted to react with Mouse, Bovine and Orangutan
Product Type
Primary Antibodies
Product Sub Types
Primary Antibodies
UNSPSC
12352203
Western Blot (WB)
1:2,000 - 1:10,000
Immunoprecipitation (IP)
2 - 10 µg/mg lysate
Target Sentence
VTA1 is involved in the endosomal multivesicular bodies (MVB) pathway. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids. VTA1 is thought to be a cofactor of VPS4A/B, which catalyzes disassembles membrane-associated ESCRT-III assemblies. It is involved in the sorting and down-regulation of EGFR (By similarity) [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q9NP79].
Product Link
http://www.bethyl.com/product/A304-828A
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