Rabbit anti-WWP1 Antibody, Affinity Purified
Brand:
A302-949A-M
- Brand
- Bethyl Laboratories
- Application
- IP
WB
- Storage Conditions
- 2 - 8° C
- Host
- Rabbit
- Conjugation
- Unconjugated
- Immunogen
- between 200 and 250
- Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide
- Reactivity
- Human
- Target
- WWP1
- Shelf Life
- 1 year from date of receipt
- Antibody Type
- Polyclonal
- Alternate Names
- AIP5, atrophin-1 interacting protein 5, Atrophin-1-interacting protein 5, HECT-type E3 ubiquitin transferase WWP1, hSDRP1, NEDD4-like E3 ubiquitin-protein ligase WWP1, Nedd-4-like ubiquitin-protein ligase, TGIF-interacting ubiquitin ligase 1, Tiul1, WW domain-containing protein 1
- Format
- Whole IgG
- Product Type
- Primary Antibodies
- Product Sub Types
- Primary Antibodies
- UNSPSC
- 12352203
- Western Blot (WB)
- 1:2,000 - 1:10,000
- Immunoprecipitation (IP)
- 2 - 5 µg/mg lysate
- Target Sentence
- WW domain-containing protein 1 (WWP1) functions as an E3 ubiquitin-protein ligase. WWP1 ubiquitinates ERBB4 isoforms JM-A CYT-1 and JM-B CYT-1, KLF2, KLF5 and TP63 and promotes their proteasomal degradation. WWP1 also ubiquitinates and promotes degradation of TGFBR1; TGFBR1 ubiquitination is enhanced by SMAD7, and WWP1 also ubiquitinates SMAD7 as well as SMAD6. [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/ Q9H0M0].
- Product Link
- http://www.bethyl.com/product/A302-949A
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