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Mouse anti-HLA-DR Monoclonal Antibody, Purified [LN3]
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Brand:
A500-022A-T
- Brand
- Bethyl Laboratories
- Application
- ICC
IHC
IHC-IF
WB
- Storage Conditions
- 2 - 8° C
- Host
- Mouse
- Conjugation
- Unconjugated
- Immunogen
- Activated human peripheral blood mononuclear cells
- Buffer
- Phosphate Buffered Saline (PBS) containing 0.09% Sodium Azide
- Reactivity
- Human
- Target
- HLA-DR
- Shelf Life
- 1 year from date of receipt
- Antibody Type
- Monoclonal
- Alternate Names
- histocompatibility antigen HLA-DR alpha, HLA class II histocompatibility antigen, DR alpha chain, HLA-DRA1, MHC class II antigen DRA
- Format
- Whole IgG
- Product Type
- Primary Antibodies
- Product Sub Types
- Primary Antibodies
- UNSPSC
- 12352203
- Western Blot (WB)
- 1:1000
- Immunohistochemistry (IHC)
- 1:100 - 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
- Immunocytochemistry (ICC)
- 1:100 - 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE cell sections.
- Immunohistochemistry-Immunofluoresence (IHC-IF)
- 1:100 to 1:500. Epitope retrieval with citrate buffer pH6.0 is recommended for FFPE cell sections.
- Target Sentence
- HLA-DRA is one of the HLA class II alpha chain paralogues. This class II molecule is a heterodimer consisting of an alpha and a beta chain, both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The alpha chain is approximately 33-35 kDa and its gene contains 5 exons. Exon 1 encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, and exon 4 encodes the transmembrane domain and the cytoplasmic tail. DRA does not have polymorphisms in the peptide binding part and acts as the sole alpha chain for DRB1, DRB3, DRB4 and DRB5 [taken from NCBI Entrez Gene (Gene ID: 3122)].
- Product Link
- http://www.bethyl.com/product/A500-022A
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