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Rabbit anti-4EBP1 Antibody, Affinity Purified

Catalog No.
A300-501A-M
Pack Size
  • 20 µl (2 blots)
  • 100 µl (10 blots)
  • 100 µl (1000 µg/ml)
Quantity
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Brand:
Specifications
A300-501A-M
Brand
Bethyl Laboratories
Application
IHC
WB
Storage Conditions
2 - 8° C
Host
Rabbit
Conjugation
Unconjugated
Immunogen
between 75 and C-term
Buffer
Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide
Reactivity
Human
Target
4EBP1
Shelf Life
1 year from date of receipt
Antibody Type
Polyclonal
Alternate Names
4EBP1, 4E-BP1, BP-1, eIF4E-binding protein 1, eukaryotic translation initiation factor 4E-binding protein 1, PHAS-I, phosphorylated heat- and acid-stable protein regulated by insulin 1
Format
Whole IgG
Presumed Reactivity
Based on 100% sequence identity, this antibody is predicted to react with Mouse and Rat
Product Type
Primary Antibodies
Product Sub Types
Primary Antibodies
UNSPSC
12352203
Western Blot (WB)
1:1,000 - 1:6,000
Immunohistochemistry (IHC)
1:5,000 - 1:20,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
Target Sentence
Eukaryotic translation initiation factor 4E-binding protein 1 (4EBP1) binds directly to eIF4E to inhibit complex assembly for translation initiation. 4EBP1 is part of a family of translation repressor proteins. 4EBP1 is directly phosphorylated by the mTORC1 complex during growth factor stimulation of cells. Phosphorylation of 4EBP1 causes its release from eIF4E to allow translation to proceed.
Product Link
http://www.bethyl.com/product/A300-501A
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