Rabbit anti-Estrogen Receptor Alpha Antibody, Affinity Purified
Brand:
A300-495A-T
- Brand
- Bethyl Laboratories
- Application
- ChIP-Seq
IHC
IP
- Storage Conditions
- 2 - 8° C
- Host
- Rabbit
- Conjugation
- Unconjugated
- Immunogen
- between 1 and 50
- Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide
- Reactivity
- Human
- Target
- Estrogen Receptor Alpha
- Shelf Life
- 1 year from date of receipt
- Antibody Type
- Polyclonal
- Alternate Names
- E2 receptor alpha, ER, Era, ER-alpha, ESR, ESRA, estradiol receptor, estrogen nuclear receptor alpha, estrogen receptor, estrogen receptor alpha E1-E2-1-2, estrogen receptor alpha E1-N2-E2-1-2, ESTRR, NR3A1, nuclear receptor subfamily 3 group A member 1, oestrogen receptor alpha
- Format
- Whole IgG
- Presumed Reactivity
- Based on 100% sequence identity, this antibody is predicted to react with Mouse and Rat
- Product Type
- Primary Antibodies
- Product Sub Types
- Primary Antibodies
- UNSPSC
- 12352203
- Western Blot (WB)
- Not recommended. Use rabbit anti-Estrogen Receptor Alpha antibody A300-498A.
- Immunoprecipitation (IP)
- 3 - 5 µg/mg lysate
- Immunohistochemistry (IHC)
- 1:1,000 - 1:5,000. Epitope retrieval with Tris-EDTA pH 9.0 is recommended for FFPE tissue sections.
- ChIP-Seq
- ChIP-Seq 4 µg/30 µg chromatin
- Target Sentence
- The estrogen receptor (ER) is the steroid-hormone nuclear receptor that binds estrogen and functions to activate genes involved in a variety of biological processes. Two forms of the ER, ER alpha and ER beta, are encoded by independent genes, and each plays different roles in gene regulation. Additional variants of ER beta have also been reported; these include ERb2, ERb3, ERb4, and ERb5. All forms of the ER have the ability to heterodimerize with each other. Differences in localization and concentrations as well as heterodimerization among the variants may serve to achieve distinct cell and tissue responses. ER alpha generally functions as an activator of transcription while ER beta functions as a repressor.
- Product Link
- http://www.bethyl.com/product/A300-495A
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