Rabbit anti-4EBP1 IHC Antibody, Affinity Purified
Brand:
IHC-00133-T
- Brand
- Bethyl Laboratories
- Application
- IHC
- Storage Conditions
- 2 - 8° C
- Host
- Rabbit
- Conjugation
- Unconjugated
- Immunogen
- between 75 and C-term
- Buffer
- Tris-buffered Saline containing 0.1% BSA and 0.09% Sodium Azide
- Reactivity
- Human, Mouse
- Target
- 4EBP1
- Shelf Life
- 1 year from date of receipt
- Antibody Type
- Polyclonal
- Alternate Names
- 4EBP1, 4E-BP1, BP-1, eIF4E-binding protein 1, eukaryotic translation initiation factor 4E-binding protein 1, PHAS-I, phosphorylated heat- and acid-stable protein regulated by insulin 1
- Format
- Whole IgG
- Product Type
- Primary Antibodies
- Product Sub Types
- Primary Antibodies
- UNSPSC
- 12352203
- Immunohistochemistry (IHC)
- 1:100 - 1:500
- Target Sentence
- Eukaryotic translation initiation factor 4E-binding protein 1 (4EBP1) binds directly to eIF4E to inhibit complex assembly for translation initiation. 4EBP1 is part of a family of translation repressor proteins. 4EBP1 is directly phosphorylated by the mTORC1 complex during growth factor stimulation of cells. Phosphorylation of 4EBP1 causes its release from eIF4E to allow translation to proceed.
- Product Link
- http://www.bethyl.com/product/IHC-00133-T
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