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Rabbit anti-DDB1 IHC Antibody, Affinity Purified

Catalog No.
IHC-00134-T
Pack Size
  • 10 µl (5+ slides)
Quantity
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Brand:
Specifications
IHC-00134-T
Brand
Bethyl Laboratories
Application
IHC
Storage Conditions
2 - 8° C
Host
Rabbit
Conjugation
Unconjugated
Immunogen
between 1100 and C-term
Buffer
Tris-buffered Saline containing 0.1% BSA and 0.09% Sodium Azide
Reactivity
Human, Mouse
Target
DDB1
Shelf Life
1 year from date of receipt
Antibody Type
Polyclonal
Alternate Names
damage-specific DNA binding protein 1, 127kDa, Damage-specific DNA-binding protein 1, DDB p127 subunit, DDBA, DNA damage-binding protein 1, DNA damage-binding protein a, HBV X-associated protein 1, UV-damaged DNA-binding factor, UV-damaged DNA-binding protein 1, UV-DDB 1, UV-DDB1, XAP1, XAP-1, xeroderma pigmentosum group E-complementing protein, XPCE, XPE, XPE-BF, XPE-binding factor
Format
Whole IgG
Product Type
Primary Antibodies
Product Sub Types
Primary Antibodies
UNSPSC
12352203
Immunohistochemistry (IHC)
1:100 - 1:500
Target Sentence
DDB1 (DNA Damage Binding Protein 1) is a subunit of the DNA damage-binding protein complex (DDB) involved in DNA repair. As part of a complex with Cul4-based ubiquitin ligase, Cul4-Ddb1 can directly modify chromatin through the ubiquitination of histones as well as ubiquitinate other chromatin bound factors. A deficiency in Cul4-Ddb1 ubiquitin ligase has been associated with xeroderma pigmentosum, a heritable disease characterized by defects in nucleotide excision repair and skin cancer development.
Product Link
http://www.bethyl.com/product/IHC-00134-T
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