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Rabbit anti-B7-H4 Recombinant Monoclonal Antibody [BLR043F]
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Brand:
A700-043-T
- Brand
- Bethyl Laboratories
- Application
- F
ICC
IHC
IHC-IF
IP
WB
- Storage Conditions
- 2 - 8° C
- Host
- Rabbit
- Conjugation
- Unconjugated
- Immunogen
- residues 30-282 (ECD)
- Buffer
- Borate Buffered Saline (BBS) pH 8.2 with 0.1% BSA and 0.09% Sodium Azide
- Reactivity
- Human
- Target
- B7-H4
- Shelf Life
- 1 year from date of receipt
- Antibody Type
- Recombinant Monoclonal
- Alternate Names
- B7 family member, H4, B7 homolog 4, B7 superfamily member 1, B7h.5, B7H4, B7-H4, B7S1, B7X, immune costimulatory protein B7-H4, PRO1291, Protein B7S1, T cell costimulatory molecule B7x, T-cell costimulatory molecule B7x, VCTN1, V-set domain-containing T-cell activation inhibitor 1
- Format
- Whole IgG
- Product Type
- Primary Antibodies
- Product Sub Types
- Primary Antibodies
- UNSPSC
- 12352203
- Western Blot (WB)
- 1:1000
- Immunoprecipitation (IP)
- 20 ul/1mg lysate
- Immunohistochemistry (IHC)
- 1:100 to 1:500. Epitope retrieval with citrate buffer pH6.0 is recommended for FFPE tissue sections.
- Immunocytochemistry (ICC)
- 1:100 to 1:500. Epitope retrieval with citrate buffer pH6.0 is recommended for FFPE cell sections.
- Immunohistochemistry-Immunofluoresence (IHC-IF)
- 1:100 to 1:500. Epitope retrieval with citrate buffer pH6.0 is recommended for FFPE tissue sections.
- Flow Cytometry (F)
- Fixed and permeabilized cells were stained with 4 µl per 1 x 10^6 cells.
- Target Sentence
- B7-H4 negatively regulates T-cell-mediated immune response by inhibiting T-cell activation, proliferation, cytokine production and development of cytotoxicity. When expressed on the cell surface of tumor macrophages, B7-H4 plays an important role, together with regulatory T-cells (Treg), in the suppression of tumor-associated antigen-specific T-cell immunity. [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/P10914].
- Product Link
- http://www.bethyl.com/product/A700-043
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