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Rabbit anti-OX40/CD134 Recombinant Monoclonal Antibody [BLR042F]
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Brand:
A700-042-T
- Brand
- Bethyl Laboratories
- Application
- F
ICC
IHC
IHC-IF
IP
WB
- Storage Conditions
- 2 - 8° C
- Host
- Rabbit
- Conjugation
- Unconjugated
- Immunogen
- residues 29-216 (ECD)
- Buffer
- Borate Buffered Saline (BBS) pH 8.2 with 0.1% BSA and 0.09% Sodium Azide
- Reactivity
- Human
- Target
- OX40/CD134
- Shelf Life
- 1 year from date of receipt
- Antibody Type
- Recombinant Monoclonal
- Alternate Names
- ACT35, ACT35 antigen, ATC35 antigen, CD antigen CD134, CD134, CD134 antigen, IMD16, lymphoid activation antigene ACT35, OX40, OX40 antigen, OX40 cell surface antigen, OX40 homologue, OX40L receptor, TAX transcriptionally-activated glycoprotein 1 receptor, tax-transcriptionally activated glycoprotein 1 receptor, tumor necrosis factor receptor superfamily member 4, TXGP1L
- Format
- Whole IgG
- Product Type
- Primary Antibodies
- Product Sub Types
- Primary Antibodies
- UNSPSC
- 12352203
- Western Blot (WB)
- 1:1000
- Immunoprecipitation (IP)
- 20 ul/1mg lysate
- Immunohistochemistry (IHC)
- 1:100 to 1:500. Epitope retrieval with citrate buffer pH6.0 is recommended for FFPE tissue sections.
- Immunocytochemistry (ICC)
- 1:100 to 1:500. Epitope retrieval with citrate buffer pH6.0 is recommended for FFPE cell sections.
- Immunohistochemistry-Immunofluoresence (IHC-IF)
- 1:100 to 1:500. Epitope retrieval with citrate buffer pH6.0 is recommended for FFPE tissue sections.
- Flow Cytometry (F)
- Fixed and permeabilized cells were stained with 4 µl per 1 x 10^6 cells.
- Target Sentence
- OX40/CD134 is a member of the TNF-receptor superfamily that has been shown to activate NF-kappaB through its interaction with adaptor proteins TRAF2 and TRAF5. Knockout studies in mice suggested that this receptor promotes the expression of apoptosis inhibitors BCL2 and BCL2lL1/BCL2-XL, and thus suppresses apoptosis. The knockout studies also suggested OX40/CD134 plays a role in CD4+ T cell response, as well as in T cell-dependent B cell proliferation and differentiation. [taken from NCBI Entrez Gene (Gene ID: 3659)].
- Product Link
- http://www.bethyl.com/product/A700-042
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