Rabbit anti-CARMIL Antibody, Affinity Purified
Brand:
A304-556A-M
- Brand
- Bethyl Laboratories
- Application
- IP
WB
- Storage Conditions
- 2 - 8° C
- Host
- Rabbit
- Conjugation
- Unconjugated
- Immunogen
- Between 1321 and 1371
- Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide
- Reactivity
- Human
- Target
- CARMIL
- Shelf Life
- 1 year from date of receipt
- Antibody Type
- Polyclonal
- Alternate Names
- capping protein regulator and myosin 1 linker protein 1, capping protein, Arp2/3 and myosin-I linker homolog 1, capping protein, Arp2/3 and myosin-I linker protein 1, capping protein, Arp2/3, and Myosin-I Linker homolog 1, CARMIL, CARMIL homolog, CARMIL1a, dJ501N12.1, dJ501N12.5, F-actin-uncapping protein LRRC16A, leucine rich repeat containing 16, leucine rich repeat containing 16A, leucine-rich repeat-containing protein 16A, LRRC16, LRRC16A, testicular tissue protein Li 107
- Format
- Whole IgG
- Presumed Reactivity
- Based on 100% sequence identity, this antibody is predicted to react with Mouse
- Product Type
- Primary Antibodies
- Product Sub Types
- Primary Antibodies
- UNSPSC
- 12352203
- Western Blot (WB)
- 1:2,000 - 1:10,000
- Immunoprecipitation (IP)
- 2 - 10 µg/mg lysate
- Target Sentence
- CARMIL binds CAPZA2 with high affinity and significantly decreases CAPZA2 affinity for actin barbed ends. It increases the rate of elongation from seeds in the presence of CAPZA2, however, seems unable to nucleate filaments. CARMIL Rapidly uncaps barbed ends capped by CAPZA2 and enhances barbed-end actin polymerization (By similarity).CARMIL may control actin dynamics in lamellipodi and be required for cell migration [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q5VZK9].
- Product Link
- http://www.bethyl.com/product/A304-556A
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