Rabbit anti-CBF-beta (isoform 1) Antibody, Affinity Purified
Brand:
A303-549A-M
- Brand
- Bethyl Laboratories
- Application
- IP
WB
- Storage Conditions
- 2 - 8° C
- Host
- Rabbit
- Conjugation
- Unconjugated
- Immunogen
- between 166 and 187
- Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide
- Reactivity
- Human, Mouse
- Target
- CBF-beta (isoform 1)
- Shelf Life
- 1 year from date of receipt
- Antibody Type
- Polyclonal
- Alternate Names
- CBF-beta, core-binding factor beta subunit, core-binding factor subunit beta, PEA2-beta, PEBP2B, PEBP2-beta, polyomavirus enhancer binding protein 2, beta subunit, Polyomavirus enhancer-binding protein 2 beta subunit, SL3/AKV core-binding factor beta subunit, SL3-3 enhancer factor 1 beta subunit, SL3-3 enhancer factor 1 subunit beta
- Format
- Whole IgG
- Product Type
- Primary Antibodies
- Product Sub Types
- Primary Antibodies
- UNSPSC
- 12352203
- Western Blot (WB)
- 1:2,000 - 1:10,000
- Immunoprecipitation (IP)
- 2 - 10 µg/mg lysate
- Target Sentence
- Core-binding factor subunit beta (CBF-beta) is the beta subunit of a heterodimeric core-binding transcription factor belonging to the PEBP2/CBF transcription factor family which master-regulates a host of genes specific to hematopoiesis (e.g., RUNX1) and osteogenesis (e.g., RUNX2). The beta subunit is a non-DNA binding regulatory subunit; it allosterically enhances DNA binding by alpha subunit as the complex binds to the core site of various enhancers and promoters, including murine leukemia virus, polyomavirus enhancer, T-cell receptor enhancers and GM-CSF promoters [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q13951].
- Product Link
- http://www.bethyl.com/product/A303-549A
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