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Rabbit anti-CD103/ITGAE Recombinant Monoclonal Antibody [BLR171J]
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Brand:
A700-171-T
- Brand
- Bethyl Laboratories
- Application
- ICC
IHC
IP
WB
- Storage Conditions
- 2 - 8° C
- Host
- Rabbit
- Conjugation
- Unconjugated
- Immunogen
- between 400 and 450
- Buffer
- Borate Buffered Saline (BBS) pH 8.2 with 0.09% Sodium Azide, BSA Free
- Reactivity
- Human
- Target
- CD103/ITGAE
- Shelf Life
- 1 year from date of receipt
- Antibody Type
- Recombinant Monoclonal
- Alternate Names
- alpha polypeptide, antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide, CD antigen CD103, CD103, HML-1 antigen, human mucosal lymphocyte antigen 1, alpha polypeptide, HUMINAE, integrin alpha-E, integrin alpha-IEL, integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1), mucosal lymphocyte 1 antigen
- Format
- Whole IgG
- Product Type
- Primary Antibodies
- Product Sub Types
- Primary Antibodies
- UNSPSC
- 12352203
- Western Blot (WB)
- 1:1,000
- Immunoprecipitation (IP)
- 6 µl/1 mg lysate
- Immunohistochemistry (IHC)
- 1:100 to 1:500. Epitope retrieval with citrate buffer pH6.0 is recommended for FFPE tissue sections.
- Immunocytochemistry (ICC)
- 1:100 to 1:500. Epitope retrieval with citrate buffer pH6.0 is recommended for FFPE cell sections.
- Target Sentence
- Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. CD103/ITGAE is an I-domain-containing alpha integrin that undergoes post-translational cleavage in the extracellular domain, yielding disulfide-linked heavy and light chains. In combination with the beta 7 integrin, CD103/ITGAE forms the E-cadherin binding integrin known as the human mucosal lymphocyte-1 antigen, and is preferentially expressed in human intestinal intraepithelial T-lymphocytes (IEL). In addition to a role in adhesion, CD103/ITGAE may serve as an accessory molecule for IEL activation. [taken from NCBI Entrez Gene (Gene ID: 3682)].
- Product Link
- http://www.bethyl.com/product/A700-171
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