A700-029-T
- Brand
- Bethyl Laboratories
- Application
- F
ICC
IP
WB
- Storage Conditions
- 2 - 8° C
- Host
- Rabbit
- Conjugation
- Unconjugated
- Immunogen
- residues 31-245 (ECD)
- Buffer
- Borate Buffered Saline (BBS) pH 8.2 with 0.09% Sodium Azide, BSA Free
- Reactivity
- Human
- Target
- CD86
- Shelf Life
- 1 year from date of receipt
- Antibody Type
- Recombinant Monoclonal
- Alternate Names
- Activation B7-2 antigen, B7.2, B70, B7-2, B-lymphocyte activation antigen B7-2, BU63, CD antigen CD86, CD28LG2, CD86 antigen (CD28 antigen ligand 2, B7-2 antigen), CTLA-4 counter-receptor B7.2, FUN-1, LAB72, T-lymphocyte activation antigen CD86
- Format
- Whole IgG
- Product Type
- Primary Antibodies
- Product Sub Types
- Primary Antibodies
- UNSPSC
- 12352203
- Western Blot (WB)
- 1:1000
- Immunoprecipitation (IP)
- 6 µl/0.5 mg lysate
- Immunocytochemistry (ICC)
- 1:100 to 1:500. Epitope retrieval with citrate buffer pH6.0 is recommended for FFPE cell sections.
- Flow Cytometry (F)
- Fixed and permeabilized cells were stained with 0.2 µl per 1 x 10^6 cells.
- Target Sentence
- CD86 is a type I membrane protein that is a member of the immunoglobulin superfamily. CD86 is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of CD86 with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of CD86 with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response [taken from NCBI Entrez Gene (Gene ID: 942)].
- Product Link
- http://www.bethyl.com/product/A700-029