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Rabbit anti-CROP/Luc7A Antibody, Affinity Purified

Catalog No.
A301-499A-T
Pack Size
  • 100 µl (1000 µg/ml)
  • 10 µl (1000 µg/ml)
Quantity
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Brand:
Specifications
A301-499A-T
Brand
Bethyl Laboratories
Application
IP
Storage Conditions
2 - 8° C
Host
Rabbit
Conjugation
Unconjugated
Immunogen
between 200 and 250
Buffer
Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide
Reactivity
Human
Target
CROP/Luc7A
Shelf Life
1 year from date of receipt
Antibody Type
Polyclonal
Alternate Names
cAMP regulatory element-associated protein 1, cisplatin resistance-associated-overexpressed protein, CRA, CREAP-1, CRE-associated protein 1, CROP, hLuc7A, LUC7A, LUC7-like 3, luc7-like protein 3, OA48-18, okadaic acid-inducible phosphoprotein OA48-18
Format
Whole IgG
Presumed Reactivity
Based on 100% sequence identity, this antibody is predicted to react with Mouse, Bovine and Orangutan
Product Type
Primary Antibodies
Product Sub Types
Primary Antibodies
UNSPSC
12352203
Western Blot (WB)
Not recommended
Immunoprecipitation (IP)
2 - 5 µg/mg lysate
Target Sentence
Cisplatin resistance-associated overexpressed protein (CROP) was originally cloned by differential display from cisplatin-resistant cells. It is an SR-related protein and the human homolog of the yeast protein, Luc7p. Luc7p is an essential protein involved in vegetative growth and 5’-splice recognition. CROP/Luc7a contains arginine- and glutamate-rich domains (RE domains) and arginine- and serine-rich domains (RS domains). It localizes to the nucleus and is distributed as speckles. CROP/Luc7a has been shown to interact with SF2/ASF, a protein involved in RNA splicing. Due to this association and the known function of its yeast homolog, CROP/Luc7a is proposed to play a role in RNA splicing.
Product Link
http://www.bethyl.com/product/A301-499A
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