A301-777A-T
- Brand
- Bethyl Laboratories
- Application
- IP
- Storage Conditions
- 2 - 8° C
- Host
- Rabbit
- Conjugation
- Unconjugated
- Immunogen
- between 150 and 200
- Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide
- Reactivity
- Human
- Target
- SDS3
- Shelf Life
- 1 year from date of receipt
- Antibody Type
- Polyclonal
- Alternate Names
- 45 kDa Sin3-associated polypeptide, SAP45, SDS3, sin3 histone deacetylase corepressor complex component SDS3, sin3A-associated protein, 45kDa, suppressor of defective silencing 3 protein homolog
- Format
- Whole IgG
- Presumed Reactivity
- Based on 100% sequence identity, this antibody is predicted to react with Mouse, Bovine and Orangutan
- Product Type
- Primary Antibodies
- Product Sub Types
- Primary Antibodies
- UNSPSC
- 12352203
- Western Blot (WB)
- Not recommended. A301-777A has not performed satisfactorily when used for WB of SDS3 in crude preparations (e.g. whole cell lysate). This antibody can be used for WB of enriched (e.g. immunoprecipitated) sources of SDS3.
- Immunoprecipitation (IP)
- 2 - 5 µg/mg lysate
- Target Sentence
- SDS3 (suppressor of defective silencing 3 protein homolog) is a component of the Sin3 histone deacetylase corepressor complex. In this complex SDS3 interacts with SIN3A to regulate gene expression via chromatin modification. Studies in mice have shown SDS3 to be important to genomic stability.
- Product Link
- http://www.bethyl.com/product/A301-777A