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Rabbit anti-hIgG4 Recombinant Monoclonal Antibody [BLR113H]

Catalog No.
A700-113-T
Pack Size
  • 10 µl (5+ tests)
  • 100 µl (50+ tests)
Quantity
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Brand:
Specifications
A700-113-T
Brand
Bethyl Laboratories
Application
IHC
WB
Storage Conditions
2 - 8° C
Host
Rabbit
Conjugation
Unconjugated
Immunogen
Between 75 and 125
Buffer
Borate Buffered Saline (BBS) pH 8.2 with 0.1% BSA and 0.09% Sodium Azide
Reactivity
Human
Target
hIgG4
Shelf Life
1 year from date of receipt
Antibody Type
Recombinant Monoclonal
Format
Whole IgG
Product Type
Primary Antibodies
Product Sub Types
Primary Antibodies
UNSPSC
12352203
Western Blot (WB)
1:1,000
Immunohistochemistry (IHC)
1:100 to 1:500. Epitope retrieval with citrate buffer pH6.0 is recommended for FFPE tissue sections.
Target Sentence
IgG4 represents only 2-5% of the human IgG subclasses in serum. IgG4 lacks effector functions, such as antibody-dependent cell-mediated cytotoxicity and complement-dependent cytotoxicity. IgG4 plays a protective role in allergy by acting as a blocking antibody, and inhibiting mast cell degranulation, but a deleterious role in malignant melanoma, by impeding IgG1-mediated anti-tumor immunity.
Product Link
http://www.bethyl.com/product/A700-113
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