Rabbit anti-Junctophilin-2 Antibody, Affinity Purified
Brand:
A304-455A-M
- Brand
- Bethyl Laboratories
- Application
- IP
WB
- Storage Conditions
- 2 - 8° C
- Host
- Rabbit
- Conjugation
- Unconjugated
- Immunogen
- between 625 and 675
- Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide
- Reactivity
- Human
- Target
- Junctophilin-2
- Shelf Life
- 1 year from date of receipt
- Antibody Type
- Polyclonal
- Alternate Names
- CMH17, JP2, JP-2, junctophilin type 2, junctophilin-2
- Format
- Whole IgG
- Product Type
- Primary Antibodies
- Product Sub Types
- Primary Antibodies
- UNSPSC
- 12352203
- Western Blot (WB)
- 1:2,000 - 1:10,000
- Immunoprecipitation (IP)
- 2 - 10 µg/mg lysate
- Target Sentence
- Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Junctophilins provide a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels. Junctophilin-2 is necessary for proper intracellular Ca(2+) signaling in cardiac myocytes via its involvement in ryanodine receptor-mediated calcium ion release, and contributes to the construction of skeletal muscle triad junctions [Taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q9BR39].
- Product Link
- http://www.bethyl.com/product/A304-455A
Related products
