Rabbit anti-KCNMA1 Antibody, Affinity Purified
Brand:
A303-409A-M
- Brand
- Bethyl Laboratories
- Application
- IP
WB
- Storage Conditions
- 2 - 8° C
- Host
- Rabbit
- Conjugation
- Unconjugated
- Immunogen
- between 450 and 500
- Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide
- Reactivity
- Human
- Target
- KCNMA1
- Shelf Life
- 1 year from date of receipt
- Antibody Type
- Polyclonal
- Alternate Names
- bA205K10.1, big potassium channel alpha subunit, BK channel, BK channel alpha subunit, BKCA alpha, BKCA alpha subunit, BKTM, CADEDS, calcium-activated potassium channel subunit alpha-1, calcium-activated potassium channel, subfamily M subunit alpha-1, hSlo, k(VCA)alpha, KCa1.1, Maxi K channel, MaxiK, maxi-K channel HSLO, mSLO1, PNKD3, potassium channel, calcium activated large conductance subfamily M alpha, member 1, potassium large conductance calcium-activated channel, subfamily M, alpha member 1, SAKCA, SLO, slo homolog, SLO1, SLO-ALPHA, slowpoke homolog, stretch-activated Kca channel, uncharacterized protein
- Format
- Whole IgG
- Presumed Reactivity
- Based on 100% sequence identity, this antibody is predicted to react with Mouse, Rat, X. laevis, Chicken, Bovine, Dog, Rabbit, Pig and Monkey
- Product Type
- Primary Antibodies
- Product Sub Types
- Primary Antibodies
- UNSPSC
- 12352203
- Western Blot (WB)
- 1:500 - 1:2,500
- Immunoprecipitation (IP)
- 2 - 10 µg/mg lysate
- Target Sentence
- KCNMA1 (potassium large conductance calcium-activated channel, subfamily M, alpha member 1) is a potassium channel activated by both membrane depolarization or increase in cytosolic Ca2+ that mediates export of K+. KCNMA1 is also activated by the concentration of cytosolic Mg2+. Its activation dampens the excitatory events that elevate the cytosolic Ca2+ concentration and/or depolarize the cell membrane. KCNMA1 therefore contributes to repolarization of the membrane potential, and plays a key role in controlling excitability in a number of systems, such as regulation of the contraction of smooth muscle, the tuning of hair cells in the cochlea, regulation of transmitter release, and innate immunity.1, maxi K channel, MaxiK, Slo-alpha, slo1, slowpoke homolog, Slo homolog, and hSlo [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q12791].
- Product Link
- http://www.bethyl.com/product/A303-409A
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