Rabbit anti-Phospho ERK1/2 (T202/Y204, T185/Y187) Antibody, Affinity Purified
Brand:
A303-608A-M
- Brand
- Bethyl Laboratories
- Application
- IP
WB
- Storage Conditions
- 2 - 8° C
- Host
- Rabbit
- Conjugation
- Unconjugated
- Immunogen
- surrounding threonine 185 and tyrosine 187
- Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide
- Reactivity
- Human
- Target
- ERK1/2, Phospho (T202/Y204, T185/Y187)
- Shelf Life
- 1 year from date of receipt
- Antibody Type
- Polyclonal
- Format
- Whole IgG
- Presumed Reactivity
- Based on 100% sequence identity, this antibody is predicted to react with Mouse, Rat, D. melanogaster, X. laevis and Bovine
- Product Type
- Primary Antibodies
- Product Sub Types
- Primary Antibodies
- UNSPSC
- 12352203
- Western Blot (WB)
- 1:1,000 - 1:5,000
- Immunoprecipitation (IP)
- Not recommended
- Target Sentence
- Extracellular signal-regulated kinase 1 (ERK1/p44), also known as mitogen-activated protein kinase 3 (MAPK3), and extracellular signal-regulated kinase 2 (ERK2/p42), also known as mitogen-activated protein kinase 1 (MAPK1), are part of a signal transduction pathway that begins with the small GTPase Ras and continues through a cascade of protein kinases that include Raf and MEK. Activation of this signaling pathway influences many cellular processes such as proliferation, differentiation and survival. ERK1 is very similar in sequence to ERK2/p42 and the activities of both ERK1 and ERK2 are usually considered together as total ERK activity. More recent evidence has shown that ERK1 and ERK2 are not functionally redundant and may have very different and specific roles.
- Product Link
- http://www.bethyl.com/product/A303-608A
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