Rabbit anti-DKC1 Antibody, Affinity Purified
Brand:
A302-591A-M
- Brand
- Bethyl Laboratories
- Application
- IP
WB
- Storage Conditions
- 2 - 8° C
- Host
- Rabbit
- Conjugation
- Unconjugated
- Immunogen
- Between 340 and 390
- Buffer
- Tris-buffered Saline containing 0.1% BSA and 0.09% Sodium Azide
- Reactivity
- Human
- Target
- DKC1
- Shelf Life
- 1 year from date of receipt
- Antibody Type
- Polyclonal
- Alternate Names
- CBF5, CBF5 homolog, DKC, DKCX, dyskeratosis congenita 1, dyskerin, Dyskerin, H/ACA ribonucleoprotein complex subunit 4, H/ACA ribonucleoprotein complex subunit DKC1, NAP57, NOLA4, nopp140-associated protein of 57 kDa, nucleolar protein family A member 4, nucleolar protein NAP57, snoRNP protein DKC1, XAP101
- Format
- Whole IgG
- Presumed Reactivity
- Based on 100% sequence identity, this antibody is predicted to react with Mouse, Rat, D. melanogaster and Chicken
- Product Type
- Primary Antibodies
- Product Sub Types
- Primary Antibodies
- UNSPSC
- 12352203
- Western Blot (WB)
- 1:2,000 - 1:10,000
- Immunoprecipitation (IP)
- 5 - 15 µg/mg lysate
- Target Sentence
- Dyskeratosis congenita 1(DKC1) is also known as dyskerin. DKC1 is required for ribosome biogenesis and telomere maintenance. It is a probable catalytic subunit of H/ACA small nucleolar ribonucleoprotein (H/ACA snoRNP) complex, which catalyzes pseudouridylation of rRNA. DKC1 is also required for correct processing or intranuclear trafficking of TERC, the RNA component of the telomerase reverse transcriptase (TERT) holoenzyme. Defects in DKC1 are a cause of dyskeratosis congenita X-linked recessive (XDKC), a rare progressive bone marrow failure syndrome [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/O60832].
- Product Link
- http://www.bethyl.com/product/A302-591A
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