A300-313A-M
- Brand
- Bethyl Laboratories
- Application
- IP
WB
- Storage Conditions
- 2 - 8° C
- Host
- Rabbit
- Conjugation
- Unconjugated
- Immunogen
- between 250 and C-term
- Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide
- Reactivity
- Human
- Target
- PIM1
- Shelf Life
- 1 year from date of receipt
- Antibody Type
- Polyclonal
- Alternate Names
- Oncogene PIM1, PIM, pim-1 kinase 44 kDa isoform, pim-1 oncogene (proviral integration site 1), proto-oncogene serine/threonine-protein kinase pim-1, serine/threonine-protein kinase pim-1
- Format
- Whole IgG
- Presumed Reactivity
- Based on 100% sequence identity, this antibody is predicted to react with Bovine and Cat
- Product Type
- Primary Antibodies
- Product Sub Types
- Primary Antibodies
- UNSPSC
- 12352203
- Western Blot (WB)
- 1:3,000 - 1:15,000
- Immunoprecipitation (IP)
- 4 - 8 µg/mg lysate
- Target Sentence
- PIM1 is a member of the PIM family of proto-oncogenes that functions as a distinct class of serine/threonine protein kinases involved in growth factor signaling. PIM1 was originally identified as a target of proviral activation in T-cell lymphomas induced by Moloney murine leukemia virus. PIM1 appears to play a role in many aspects of cell growth, proliferation, and apoptosis. PIM1 is required for efficient cell cycle induction of peripheral T-cells in response to IL-2 signaling. PIM1 substrates include p21 cip1/waf1, CDC25A, PTP-U2, NuMA, and PAP-1.
- Product Link
- http://www.bethyl.com/product/A300-313A