A305-144A-M
- Brand
- Bethyl Laboratories
- Application
- IP
WB
- Storage Conditions
- 2 - 8° C
- Host
- Rabbit
- Conjugation
- Unconjugated
- Immunogen
- Between 86 and 136
- Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide
- Reactivity
- Human
- Target
- RPS19BP1/AROS
- Shelf Life
- 1 year from date of receipt
- Antibody Type
- Polyclonal
- Alternate Names
- 40S ribosomal protein S19-binding protein 1, active regulator of SIRT1, AROS, homolog of mouse S19 binding protein, RPS19-binding protein 1, S19BP
- Format
- Whole IgG
- Product Type
- Primary Antibodies
- Product Sub Types
- Primary Antibodies
- UNSPSC
- 12352203
- Western Blot (WB)
- 1:2,000 - 1:10,000
- Immunoprecipitation (IP)
- Not recommended
- Target Sentence
- The protein active regulator of SIRT1, also known as Ribosomal Protein S19 Binding Protein 1, is a direct regulator of SIRT1. By enhancing SIRT1-mediated deacetylation of p53/TP53 this protein participates in the inhibition of p53/TP53-mediated transcriptional activity. Active regulator of SIRT1 is encoded for by the gene RPS19BP1, also known as AROS or S19BP [taken from UniProtKB (Entry: Q86WX3)].
- Product Link
- http://www.bethyl.com/product/A305-144A