Rabbit anti-SMAR1/BANP Antibody, Affinity Purified
Brand:
A300-279A-M
- Brand
- Bethyl Laboratories
- Application
- IHC
IP
WB
- Storage Conditions
- 2 - 8° C
- Host
- Rabbit
- Conjugation
- Unconjugated
- Immunogen
- between 425 and C-term
- Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide
- Reactivity
- Human, Mouse
- Target
- SMAR1/BANP
- Shelf Life
- 1 year from date of receipt
- Antibody Type
- Polyclonal
- Alternate Names
- BEN domain-containing protein 1, BEND1, Btg3-associated nuclear protein, protein BANP, scaffold/matrix-associated region-1-binding protein, SMAR1, SMARBP1
- Format
- Whole IgG
- Presumed Reactivity
- Based on 100% sequence identity, this antibody is predicted to react with Bovine
- Product Type
- Primary Antibodies
- Product Sub Types
- Primary Antibodies
- UNSPSC
- 12352203
- Western Blot (WB)
- 1:10,000 - 1:25,000
- Immunoprecipitation (IP)
- 1:500 - 1:2,500
- Immunohistochemistry (IHC)
- 1:2,000 - 1:10,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
- Target Sentence
- SMAR1/BANP was identified as a protein that binds the scaffold/matrix associated region of the T-cell receptor beta locus (SMAR1) and as a protein that interacts with BTG3, a member of structurally related proteins that regulate cell proliferation (BANP- BTG-associated nuclear protein). SMAR1/BANP is a DNA binding protein that is reported to be a tumor suppressor and transcriptional repressor. SMAR1/BANP can down-regulate cyclin D1 transcription by binding to the cyclin D1 promoter and through its interaction with HDAC1 (histone deacetylase 1). SMAR1 has also been shown to interact with p53 and modulate its activity.
- Product Link
- http://www.bethyl.com/product/A300-279A
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