Rabbit anti-TARBP1 Antibody, Affinity Purified
Brand:
A303-632A-M
- Brand
- Bethyl Laboratories
- Application
- IP
WB
- Storage Conditions
- 2 - 8° C
- Host
- Rabbit
- Conjugation
- Unconjugated
- Immunogen
- Between 1571 and 1621
- Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide
- Reactivity
- Human
- Target
- TARBP1
- Shelf Life
- 1 year from date of receipt
- Antibody Type
- Polyclonal
- Alternate Names
- probable methyltransferase TARBP1, TAR (HIV) RNA-binding protein 1, TAR RNA loop binding protein, TAR RNA-binding protein 1, TAR RNA-binding protein of 185 kDa, TRM3, TRMT3, tRNA methyltransferase 3 homolog, TRP185, TRP-185
- Format
- Whole IgG
- Product Type
- Primary Antibodies
- Product Sub Types
- Primary Antibodies
- UNSPSC
- 12352203
- Western Blot (WB)
- 1:1,000 - 1:5,000
- Immunoprecipitation (IP)
- 2 - 10 µg/mg lysate
- Target Sentence
- TAR RNA-binding protein 1 (TARBP1) is a probable S-adenosyl-L-methionine-dependent methyltransferase which methylates RNA molecules such as tRNAs. In case of infection by HIV-1, it binds to the loop region of TAR RNA, a region also bound by RNA polymerase II. Binding of TARBP1 and RNA polymerase II to HIV-1 TAR RNA is mutually exclusive, suggesting that TARBP1 may function alone or in conjunction with HIV-1 Tat to disengage RNA polymerase II from HIV-1 TAR RNA. TARBP1 may act by methylating HIV-1 TAR RNA [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/ Q13395].
- Product Link
- http://www.bethyl.com/product/A303-632A
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