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Rabbit anti-TIGAR Antibody, Affinity Purified

Catalog No.
A302-286A-T
Pack Size
  • 100 µl (1000 µg/ml)
  • 10 µl (1000 µg/ml)
Quantity
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Brand:
Specifications
A302-286A-T
Brand
Bethyl Laboratories
Application
IHC
IP
Storage Conditions
2 - 8° C
Host
Rabbit
Conjugation
Unconjugated
Immunogen
Between 220 and 270
Buffer
Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide
Reactivity
Human
Target
TIGAR
Shelf Life
1 year from date of receipt
Antibody Type
Polyclonal
Alternate Names
C12orf5, FR2BP, fructose-2,6-bisphosphatase TIGAR, fructose-2,6-bisphosphate 2-phosphatase, probable fructose-2,6-bisphosphatase TIGAR, TP53-induced glycolysis and apoptosis regulator, TP53-induced glycolysis regulatory phosphatase, transactivated by NS3TP2 protein
Format
Whole IgG
Product Type
Primary Antibodies
Product Sub Types
Primary Antibodies
UNSPSC
12352203
Western Blot (WB)
Not recommended. Use rabbit anti-TIGAR antibody A302-285A.
Immunoprecipitation (IP)
10 µg/mg lysate
Immunohistochemistry (IHC)
1:500 - 1:2,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
Target Sentence
TIGAR (TP53-induced glycolysis and apoptosis regulator) is a protein with sequence similarity to the bisphosphate domain of the glycolytic enzyme that degrades fructose-2,6-bisphosphate. The protein functions by blocking glycolysis and directing the pathway into the pentose phosphate shunt. Expression of this protein also protects cells from DNA damaging reactive oxygen species and provides some protection from DNA damage-induced apoptosis [taken from NCBI GeneID:57103].
Product Link
http://www.bethyl.com/product/A302-286A
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