A700-156-T
- Brand
- Bethyl Laboratories
- Application
- ICC
IP
WB
- Storage Conditions
- 2 - 8° C
- Host
- Rabbit
- Conjugation
- Unconjugated
- Immunogen
- between 1 and 50
- Buffer
- Phosphate Buffered Saline (PBS) containing 0.2% BSA and 0.09% Sodium Azide
- Reactivity
- Human
- Target
- TWIST1
- Shelf Life
- 1 year from date of receipt
- Antibody Type
- Recombinant Monoclonal
- Alternate Names
- ACS3, B-HLH DNA binding protein, bHLHa38, BPES2, BPES3, class A basic helix-loop-helix protein 38, CRS, CRS1, CSO, H-twist, SCS, SWCOS, TWIST, twist basic helix-loop-helix transcription factor 1, twist homolog 1, TWIST homolog of drosophila, twist-related protein 1
- Format
- Whole IgG
- Product Type
- Primary Antibodies
- Product Sub Types
- Primary Antibodies
- UNSPSC
- 12352203
- Western Blot (WB)
- 1:1,000
- Immunoprecipitation (IP)
- 20 µl/1 mg lysate
- Immunocytochemistry (ICC)
- 1:100 to 1:500. Epitope retrieval with citrate buffer pH6.0 is recommended for FFPE cell sections.
- Target Sentence
- TWIST1 is a basic helix-loop-helix (bHLH) transcription factor that plays an important role in embryonic development. TWIST1 forms both homodimers and heterodimers that bind to DNA E box sequences and regulate the transcription of genes involved in cranial suture closure during skull development. TWIST1 may also regulate neural tube closure, limb development and brown fat metabolism. The TWIST1 gene is hypermethylated and overexpressed in multiple human cancers, and the encoded protein promotes tumor cell invasion and metastasis, as well as metastatic recurrence. [taken from NCBI Entrez Gene (Gene ID: 7291)].
- Product Link
- http://www.bethyl.com/product/A700-156