Rabbit anti-WNK1 Antibody, Affinity Purified
Brand:
A301-515A-M
- Brand
- Bethyl Laboratories
- Application
- IP
WB
- Storage Conditions
- 2 - 8° C
- Host
- Rabbit
- Conjugation
- Unconjugated
- Immunogen
- Between 2100 and 2150
- Buffer
- Tris-buffered Saline containing 0.1% BSA and 0.09% Sodium Azide
- Reactivity
- Human, Mouse
- Target
- WNK1
- Shelf Life
- 1 year from date of receipt
- Antibody Type
- Polyclonal
- Alternate Names
- erythrocyte 65 kDa protein, HSAN2, HSN2, hWNK1, KDP, Kinase deficient protein, p65, PPP1R167, PRKWNK1, prostate-derived sterile 20-like kinase, Protein kinase lysine-deficient 1, protein kinase with no lysine 1, protein phosphatase 1, regulatory subunit 167, PSK, serine/threonine-protein kinase WNK1, serine/threonine-protein kinase WNK1 1, serine/threonine-protein kinase WNK1 2, WNK lysine deficient protein kinase 1 isoform
- Format
- Whole IgG
- Presumed Reactivity
- Based on 100% sequence identity, this antibody is predicted to react with Rat
- Product Type
- Primary Antibodies
- Product Sub Types
- Primary Antibodies
- UNSPSC
- 12352203
- Western Blot (WB)
- 1:2,000 - 1:10,000
- Immunoprecipitation (IP)
- 2 - 10 µg/mg lysate
- Target Sentence
- WNK1 (with no lysine 1) is a member of the WNK family of serine-threonine kinases. The WNK family of kinases has been observed to play a role in several cellular processes which include ion balance, signal transduction, survival, proliferation and organ development. WNK1 appears to be important to ion homeostasis. Mutations in WNK1 cause pseudohypoaldosteronism type II (PHA II), also called Gordon’s syndrome, an autosomal dominant disease characterized by defects in ion transport in the nephron that result in hypertension and hyperkalemia. WNK1 has been reported to regulate sodium and chloride ion transport by influencing the activity of another WNK family member, WNK4. WNKF1 has also been observed to regulate ion homeostasis independent of WNK4.
- Product Link
- http://www.bethyl.com/product/A301-515A
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