A302-337A-M
- Brand
- Bethyl Laboratories
- Application
- IP
WB
- Storage Conditions
- 2 - 8° C
- Host
- Rabbit
- Conjugation
- Unconjugated
- Immunogen
- between 575 and 625
- Buffer
- Tris-buffered Saline containing 0.1% BSA and 0.09% Sodium Azide
- Reactivity
- Human
- Target
- c-Cbl
- Shelf Life
- 1 year from date of receipt
- Antibody Type
- Polyclonal
- Alternate Names
- Cas-Br-M (murine) ecotropic retroviral transforming sequence, casitas B-lineage lymphoma proto-oncogene, Cbl proto-oncogene, E3 ubiquitin protein ligase, CBL2, C-CBL, E3 ubiquitin-protein ligase CBL, FRA11B, fragile site, folic acid type, rare, fra(11)(q23.3), NSLL, oncogene CBL2, proto-oncogene c-Cbl, RING finger protein 55, RING-type E3 ubiquitin transferase CBL, RNF55, signal transduction protein CBL
- Format
- Whole IgG
- Product Type
- Primary Antibodies
- Product Sub Types
- Primary Antibodies
- UNSPSC
- 12352203
- Western Blot (WB)
- 1:2,000 - 1:10,000
- Immunoprecipitation (IP)
- 2 - 5 µg/mg lysate
- Target Sentence
- The cbl oncogene was first identified as part of a transforming retrovirus which induces mouse pre-B and pro-B cell lymphomas. As an adaptor protein for receptor protein-tyrosine kinases, it positively regulates receptor protein-tyrosine kinase ubiquitination in a manner dependent upon its variant SH2 and RING finger domains. Ubiquitination of receptor protein-tyrosine kinases terminates signaling by marking active receptors for degradation [taken from NCBI GeneID:867].
- Product Link
- http://www.bethyl.com/product/A302-337A