Rabbit anti-DAB2IP Antibody, Affinity Purified
Brand:
A302-439A-M
- Brand
- Bethyl Laboratories
- Application
- IP
WB
- Storage Conditions
- 2 - 8° C
- Host
- Rabbit
- Conjugation
- Unconjugated
- Immunogen
- between 850 and 900
- Buffer
- Tris-buffered Saline containing 0.1% BSA and 0.09% Sodium Azide
- Reactivity
- Human, Mouse
- Target
- DAB2IP
- Shelf Life
- 1 year from date of receipt
- Antibody Type
- Polyclonal
- Alternate Names
- AF9Q34, AIP1, AIP-1, ASK1-interacting protein 1, ASK-interacting protein 1, DAB2 interaction protein, DAB2-interacting protein, DIP1/2, disabled homolog 2-interacting protein, DOC-2/DAB2 interactive protein, DOC-2/DAB-2 interactive protein, nGAP-like protein
- Format
- Whole IgG
- Presumed Reactivity
- Based on 100% sequence identity, this antibody is predicted to react with Rat
- Product Type
- Primary Antibodies
- Product Sub Types
- Primary Antibodies
- UNSPSC
- 12352203
- Western Blot (WB)
- 1:2,000 - 1:10,000
- Immunoprecipitation (IP)
- 2 - 5 µg/mg lysate
- Target Sentence
- DAB2-interacting protein (DAB2IP) functions as a Ras GTPase-activating protein. Through its interaction with MAP3K5, it disrupts the association of MAP3K5 with the inhibitory 14-3-3 complex. DAB2IP also Mediates TNF/TRAF2-induced MAP3K5-JNK activation, while it inhibits CHUK-NF-kappa-B signaling. DAB2IP may act as a tumor suppressor gene [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q5VWQ8].
- Product Link
- http://www.bethyl.com/product/A302-439A
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