Rabbit anti-GLI3 Antibody, Affinity Purified
Brand:
A303-417A-M
- Brand
- Bethyl Laboratories
- Application
- IHC
IP
WB
- Storage Conditions
- 2 - 8° C
- Host
- Rabbit
- Conjugation
- Unconjugated
- Immunogen
- Between 875 and 925
- Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide
- Reactivity
- Human
- Target
- GLI3
- Shelf Life
- 1 year from date of receipt
- Antibody Type
- Polyclonal
- Alternate Names
- ACLS, GCPS, GLI3 form of 190 kDa, GLI3 full-length protein, GLI3-190, GLI3FL, GLI-Kruppel family member GLI3, glioma-associated oncogene family zinc finger 3, oncogene GLI3, PAPA, PAP-A, PAPA1, PAPB, PHS, PPDIV, transcriptional activator GLI3, zinc finger protein GLI3
- Format
- Whole IgG
- Presumed Reactivity
- Based on 100% sequence identity, this antibody is predicted to react with Mouse and Chimpanzee
- Product Type
- Primary Antibodies
- Product Sub Types
- Primary Antibodies
- UNSPSC
- 12352203
- Western Blot (WB)
- 1:2,000 - 1:10,000
- Immunoprecipitation (IP)
- 2 - 10 µg/mg lysate
- Immunohistochemistry (IHC)
- 1:500 - 1:2,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
- Target Sentence
- GLI3 (GLI family zinc finger 3) plays a role in limb development and has a dual function as a transcriptional activator and a repressor of the sonic hedgehog (Shh) pathway. After phosphorylation and nuclear translocation, the full-length form of GLI3 (GLI3FL), acts as an activator (GLI3A) while the C-terminally truncated form (GLI3R) acts as a repressor [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/ P10071].
- Product Link
- http://www.bethyl.com/product/A303-417A
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